49ers lose to Rams on final play

Colin Kaepernick endured a career-high eight sacks and lost a fumble at the St. Louis Rams' goal line with two seconds remaining Sunday, sealing a stunning 13-10 49ers defeat at Levi's Stadium. A replay review failed to reverse the ruling that Kaepernick had fumbled while trying to score on a quarterback sneak, sending the 49ers to their second straight defeat.

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